The Complex and Diverse Genetic Architecture of Dilated Cardiomyopathy

Genetic Testing for Dilated Cardiomyopathy

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Genetic mutations and mechanisms in dilated cardiomyopathy.

Genetic mutations account for a significant percentage of cardiomyopathies, which are a leading cause of congestive heart failure. In hypertrophic cardiomyopathy (HCM), cardiac output is limited by the thickened myocardium through impaired filling and outflow. Mutations in the genes encoding the thick filament components myosin heavy chain and myosin binding protein C (MYH7 and MYBPC3) together...

Role of Genetic Factors in Dilated Cardiomyopathy

Role of Genetic Factors in Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by cardiac chamber enlargement and impaired systolic (and almost always diastolic) function. It is usually associated with heart failure, arrhythmias and/or conduction system disease and thromboembolic disease but may also be asymptomatic. DCM is diagnosed in the presence of left ventricular enlargement and systolic dysfunctio...

phylogeography and genetic diversity of the lesser mouse- eared bat (myotis blythii) in iran

in current study, 63 samples of bat populations collected from differ regions were used for evaluating the geographic variations. twenty cranial and dental characters for traditional morphometric and landmarks method on the ventral, dorsal skull and mandible for geometry morphometric studies were used. statistical analyses of traditional morphometric and geometry morphometric data indicated low...